Plectus - a stepping stone in embryonic cell lineage evolution of nematodes

The evolution of cell lineage in nematodes.

The invariant development of free-living nematodes combined with the extensive knowledge of Caenorhabditis elegans developmental biology provides an experimental system for an analysis of the evolution of developmental mechanisms. We have collected a number of new nematode species from soil samples. Most are easily cultured and their development can be analyzed at the level of individual cells ...

Evolution of altruism in stepping-stone populations with overlapping generations.

We study the evolution of altruism in one- and two-dimensional stepping-stone populations with discrete overlapping generations. We find that increasing survival probability facilitates the evolution of altruism, in agreement with recent results for a patch-structured population. We allow the altruistic behaviour to affect either fecundity or survival probability. In the first case, altruism is...

Genetic demixing and evolution in linear stepping stone models.

Results for mutation, selection, genetic drift, and migration in a one-dimensional continuous population are reviewed and extended. The population is described by a continuous limit of the stepping stone model, which leads to the stochastic Fisher-Kolmogorov-Petrovsky-Piscounov equation with additional terms describing mutations. Although the stepping stone model was first proposed for populati...

A Stepping Stone to Pluripotency

Somatic cells can be reprogrammed into pluripotent stem cells via either expression of transcription factors or addition of small molecule chemicals only. Zhao et al. reveal a unique intermediate state during chemical reprogramming allowing a significant improvement in its efficiency and kinetics.

Stepping Stone Detection Analysis